Nephritic Syndrome 腎病綜合症

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Nephritic syndrome can be caused by a wide variety of glomerular diseases.

It may follow bacterial or viral infections, malignant tumors and administration of some drugs.

Some immune diseases, such as systems lupus erythematosus, allergic purpura and diabetes mellitus can be complicated by nephritic syndrome.

Main points of diagnosis:

1 Heavy proteinuria, accompanied with edema and hypoproteinemia, are three major manifestation of this syndrome.

Urinary protein excretion exceeds 3.5g/day.

The serum albumin is lower than 30g/Liter.

Severe edema may appear if serum albumin is lower than 15g/Liter.

2 The alteration of blood pressure varies with different types of the disease.

Hyperlipemia is common, particularly increased cholesterol.

3 About 75% of cases with nephritic syndrome are caused by primary glomerular diseases.

In children nearly 80% of cases are nephritic syndrome of minute lesion type. The rest are secondary to other diseases.


腎病綜合症可中由多種腎小球病變所引起,亦可繼發于細菌,病毒等感染,惡性腫瘤,或使用某些藥物以后.

部份免疫性疾病,如系統性紅斑狼瘡,過敏性紫癜,糖尿病等,亦可併發本症.

診斷要點:

1 大量蛋白尿伴浮腫及低蛋白血症是本病三大特點.

尿蛋白>3.5g/日,血漿白蛋白<30g/公升,低于15g/公升可出現嚴重浮腫.

2 血壓改變隨病種而異,高血脂症常見,以膽固醇增高為主.

3 約75%患者由原發性腎小球疾病所致,兒童中80%為微小病變型腎病,餘多為繼發性病變.


肾病综合症可中由多种肾小球病变所引起,亦可继发于细菌,病毒等感染,恶性肿瘤,或使用某些药物以后.

部份 免疫性疾病,如系统性红斑狼疮,过敏性紫癜,糖尿病等,亦可并发本症.

诊断要点:

1大量蛋白尿伴浮肿及低蛋白血症是本病三大特点.

尿蛋白>3.5g/日,血浆白蛋白<30g/公升,低于15g/公升可出 现严重浮肿.

2血压改变随病种而异,高血脂症常见,以胆固醇增高为主.

3约75%患者由原发性肾小球疾病所致,儿童中80%为微小病变型肾病,余多为继发性病变.




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